Mutation profiles of synchronous colorectal cancers from a patient with Lynch syndrome suggest distinct oncogenic pathways

Patients with Lynch syndrome often present with multiple synchronous or metachronous colorectal cancers (CRCs). The presence of multiple CRCs with distinct genetic profiles and driver mutations could complicate treatment as each cancer may respond differently to therapy. Studies of sporadic CRCs sug...

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Foilsithe in:J Gastrointest Oncol
Main Authors: Wheeler, Scott R., Shi, Chanjuan, Holt, Jonathan A., Vnencak-Jones, Cindy L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: AME Publishing Company 2016
Ábhair:
Case Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880766/
https://ncbi.nlm.nih.gov/pubmed/27284491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.01.07
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