Combination of 5‐aminolevulinic acid and ferrous ion reduces plasma glucose and hemoglobin A1c levels in Zucker diabetic fatty rats

Mitochondrial dysfunction is associated with type 2 diabetes mellitus (T2DM). 5‐Aminolevulinic acid (ALA), a natural amino acid produced only in the mitochondria, is a precursor of heme. Cytochromes that contain heme play an important role in aerobic energy metabolism. Thus, ALA may help reduce T2DM...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Hara, Takeshi, Koda, Aya, Nozawa, Naoko, Ota, Urara, Kondo, Hikaru, Nakagawa, Hitoshi, Kamiya, Atsuko, Miyashita, Kazutoshi, Itoh, Hiroshi, Nakajima, Motowo, Tanaka, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880722/
https://ncbi.nlm.nih.gov/pubmed/27239432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12048
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