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Pleiotropic Effects of IL-2 on Cancer: Its Role in Cervical Cancer

IL-2 receptor (IL-2R) signalling is critical for normal lymphocyte proliferation, but its role in cervical cancer is not fully understood. The receptor is composed of three chains: IL-2α, IL-2β, and IL-2γ. Intracellular signalling is initiated by ligand-induced heterodimerization of the IL-2β and IL...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Valle-Mendiola, Arturo, Gutiérrez-Hoya, Adriana, Lagunas-Cruz, María del Carmen, Weiss-Steider, Benny, Soto-Cruz, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880719/
https://ncbi.nlm.nih.gov/pubmed/27293315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2849523
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