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Translational capacity of a cell is determined during transcription elongation via the Ccr4-Not complex

Current understanding of gene expression considers transcription and translation to be independent processes. Challenging this notion, we found that translation efficiency is determined during transcription elongation through imprinting of mRNAs with Not1, the central scaffold of the Ccr4-Not comple...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Gupta, Ishaan, Villanyi, Zoltan, Kassem, Sari, Hughes, Christopher, Panasenko, Olesya O., Steinmetz, Lars M., Collart, Martine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880543/
https://ncbi.nlm.nih.gov/pubmed/27184853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.055
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