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Disparate Response to Methotrexate in Stem versus Non-Stem Cells
Methotrexate (MTX) is a commonly used chemotherapeutic agent that kills cancer cells by binding dihydrofolate reductase (DHFR) as a competitive inhibitor. Due to its non-selectivity, MTX also impairs normal (non-cancerous) cell function and causes long-term damage to healthy tissue. These consequenc...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Stem Cell Rev |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880537/ https://ncbi.nlm.nih.gov/pubmed/26815725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-016-9645-9 |
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