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UV-Induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis

Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts usually created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine. Surprisingly we found that, in melanocytes, CPDs were generated for hours after UVA or UVB exposu...

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Détails bibliographiques
Publié dans:Toxicol Pathol
Auteur principal: Brash, Douglas E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880532/
https://ncbi.nlm.nih.gov/pubmed/26951162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623316632072
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