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UV-Induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis

Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts usually created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine. Surprisingly we found that, in melanocytes, CPDs were generated for hours after UVA or UVB exposu...

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Detalles Bibliográficos
Publicado en:Toxicol Pathol
Autor Principal: Brash, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880532/
https://ncbi.nlm.nih.gov/pubmed/26951162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623316632072
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