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Autophagy promotes focal adhesion disassembly and cell motility of metastatic tumor cells through the direct interaction of paxillin with LC3

Autophagy is a conserved catabolic process that plays a housekeeping role in eliminating protein aggregates and organelles and is activated during nutrient deprivation to generate metabolites and energy. Autophagy plays a significant role in tumorigenesis, although opposing context-dependent functio...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Sharifi, Marina N., Mowers, Erin E., Drake, Lauren E., Collier, Chris, Chen, Hong, Zamora, Marta, Mui, Stephanie, Macleod, Kay F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880529/
https://ncbi.nlm.nih.gov/pubmed/27184837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.065
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