Elastin-derived peptides promote abdominal aortic aneurysm formation by modulating M1/M2 macrophage polarization()

Abdominal aortic aneurysm (AAA) is a dynamic vascular disease characterized by inflammatory cell invasion and extracellular matrix (ECM) degradation. Damage to elastin in the ECM results in release of elastin-derived peptides (EDPs), which are chemotactic for inflammatory cells such as monocytes. Th...

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Udgivet i:J Immunol
Main Authors: Dale, Matthew A, Xiong, Wanfen, Carson, Jeffrey S, Suh, Melissa K, Karpisek, Andrew D., Meisinger, Trevor M., Casale, George P., Baxter, B. Timothy
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880455/
https://ncbi.nlm.nih.gov/pubmed/27183603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502454
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