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The G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Nuclear Estrogen Receptor Activity and Stimulates Novel Phosphoproteomic Signatures

Estrogen exerts cellular effects through both nuclear (ESR1 and ESR2) and membrane-bound estrogen receptors (G-protein coupled estrogen receptor, GPER); however, it is unclear if they act independently or engage in crosstalk to influence hormonal responses. To investigate each receptor’s role in pro...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Smith, L. Cody, Ralston-Hooper, Kimberly J., Ferguson, P. Lee, Sabo-Attwood, Tara
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880142/
https://ncbi.nlm.nih.gov/pubmed/27026707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw057
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