Proinflammatory Cytokine Infusion Attenuates LH's Feedforward on Testosterone Secretion: Modulation by Age

CONTEXT: In the experimental animal, inflammatory signals quench LH's feedforward drive of testosterone (T) secretion and appear to impair GnRH-LH output. The degree to which such suppressive effects operate in the human is not known. OBJECTIVE: To test the hypothesis that IL-2 impairs LH'...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Veldhuis, Johannes, Yang, Rebecca, Roelfsema, Ferdinand, Takahashi, Paul
Format: Artigo
Language:Inglês
Published: Endocrine Society 2016
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880122/
https://ncbi.nlm.nih.gov/pubmed/26600270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-3611
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