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The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling

Polymorphisms in FKBP51 are associated with stress-related psychiatric disorders and influence the severity of pain symptoms experienced after trauma. Here, we report that FKBP51 (FK506 binding protein 51) is crucial for the full development and maintenance of long-term pain states and that this is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Transl Med
मुख्य लेखकों: Maiarù, Maria, Tochiki, Keri K., Cox, Marc B., Annan, Leonette V., Bell, Christopher G., Feng, Xixi, Hausch, Felix, Géranton, Sandrine M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880036/
https://ncbi.nlm.nih.gov/pubmed/26865567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aab3376
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