PET neuroimaging studies of [(18)F]CABS13 in a double transgenic mouse model of Alzheimer’s disease and non-human primates

Fluorine-18 labeled 2-fluoro-8-hydroxyquinoline ([(18)F]CABS13) is a promising positron emission tomography (PET) radiopharmaceutical based on a metal chelator developed to probe the “metal hypothesis of Alzheimer’s disease”. Herein, a practical radiosynthesis of [(18)F]CABS13 was achieved by radiof...

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Udgivet i:ACS Chem Neurosci
Main Authors: Liang, Steven H., Holland, Jason P., Stephenson, Nickeisha A., Kassenbrock, Alina, Rotstein, Benjamin H., Daignault, Cory P., Lewis, Rebecca, Collier, Lee, Hooker, Jacob M., Vasdev, Neil
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879824/
https://ncbi.nlm.nih.gov/pubmed/25776827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00055
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