Intramyocardial VEGF-B(167) Gene Delivery Delays the Progression Towards Congestive Failure in Dogs With Pacing-Induced Dilated Cardiomyopathy

RATIONALE: Vascular endothelial growth factor (VEGF)-B selectively binds VEGF receptor (VEGFR)-1, a receptor that does not mediate angiogenesis, and is emerging as a major cytoprotective factor. OBJECTIVE: To test the hypothesis that VEGF-B exerts non–angiogenesis-related cardioprotective effects in...

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Veröffentlicht in:Circ Res
Hauptverfasser: Pepe, Martino, Mamdani, Mohammed, Zentilin, Lorena, Csiszar, Anna, Qanud, Khaled, Zacchigna, Serena, Ungvari, Zoltan, Puligadda, Uday, Moimas, Silvia, Xu, Xiaobin, Edwards, John G., Hintze, Thomas H., Giacca, Mauro, Recchia, Fabio A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879815/
https://ncbi.nlm.nih.gov/pubmed/20431055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.220855
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