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Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study

Oxidative stress is involved in the pathophysiology of many cardiovascular disorders, such as hypertension and atherosclerosis. NRF2 is the primary transcriptional regulator of several antioxidant genes, including that of sulfiredoxin (SRXN1). The association of genotypes of NRF2 and SRXN1 with card...

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Dades bibliogràfiques
Publicat a:Int J Med Sci
Autors principals: Kunnas, Tarja, Määttä, Kirsi, Nikkari, Seppo T
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879764/
https://ncbi.nlm.nih.gov/pubmed/27226772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.14849
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