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Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease

INTRODUCTION: Early life lead (Pb) exposure results in a latent increase in Alzheimer's disease (AD)–related proteins, and cognitive deficits late in life in both rodents and primates. This study was conducted to investigate if these late life changes were accompanied by epigenetic alterations....

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Detalles Bibliográficos
Publicado en:Alzheimers Dement (Amst)
Main Authors: Eid, Aseel, Bihaqi, Syed Waseem, Renehan, William E., Zawia, Nasser H.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879653/
https://ncbi.nlm.nih.gov/pubmed/27239543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2016.02.002
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