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Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease

INTRODUCTION: Early life lead (Pb) exposure results in a latent increase in Alzheimer's disease (AD)–related proteins, and cognitive deficits late in life in both rodents and primates. This study was conducted to investigate if these late life changes were accompanied by epigenetic alterations....

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Publicado en:Alzheimers Dement (Amst)
Autores principales: Eid, Aseel, Bihaqi, Syed Waseem, Renehan, William E., Zawia, Nasser H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879653/
https://ncbi.nlm.nih.gov/pubmed/27239543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2016.02.002
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