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Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease

INTRODUCTION: Early life lead (Pb) exposure results in a latent increase in Alzheimer's disease (AD)–related proteins, and cognitive deficits late in life in both rodents and primates. This study was conducted to investigate if these late life changes were accompanied by epigenetic alterations....

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Bibliographic Details
Published in:Alzheimers Dement (Amst)
Main Authors: Eid, Aseel, Bihaqi, Syed Waseem, Renehan, William E., Zawia, Nasser H.
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879653/
https://ncbi.nlm.nih.gov/pubmed/27239543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2016.02.002
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