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Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease

INTRODUCTION: Early life lead (Pb) exposure results in a latent increase in Alzheimer's disease (AD)–related proteins, and cognitive deficits late in life in both rodents and primates. This study was conducted to investigate if these late life changes were accompanied by epigenetic alterations....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Dement (Amst)
Hauptverfasser: Eid, Aseel, Bihaqi, Syed Waseem, Renehan, William E., Zawia, Nasser H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879653/
https://ncbi.nlm.nih.gov/pubmed/27239543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2016.02.002
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