Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Behçet’s disease

The TAM kinase (Tyro3, Axl, Mer) and its two ligands (Gas6 and protein S) have been shown to play an important regulatory role in the innate immune response. The present study aimed to investigate whether the tag single-nucleotide polymorphisms (tag SNPs) of these 5 protein-coding genes are associat...

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Udgivet i:Sci Rep
Main Authors: Qin, Jieying, Li, Lin, Zhang, Donglei, Yu, Hongsong, Tan, Handan, Zhang, Jun, Deng, Bolin, Kijlstra, Aize, Yang, Peizeng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879572/
https://ncbi.nlm.nih.gov/pubmed/27222359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26662
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