Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene bla(KPC)

The recent widespread emergence of carbapenem resistance in Enterobacteriaceae is a major public health concern, as carbapenems are a therapy of last resort against this family of common bacterial pathogens. Resistance genes can mobilize via various mechanisms, including conjugation and transpositio...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Sheppard, Anna E., Stoesser, Nicole, Wilson, Daniel J., Sebra, Robert, Kasarskis, Andrew, Anson, Luke W., Giess, Adam, Pankhurst, Louise J., Vaughan, Alison, Grim, Christopher J., Cox, Heather L., Yeh, Anthony J., Sifri, Costi D., Walker, A. Sarah, Peto, Tim E., Crook, Derrick W., Mathers, Amy J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Epidemiology and Surveillance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879409/
https://ncbi.nlm.nih.gov/pubmed/27067320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00464-16
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