Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.

Trypanosoma brucei parasites are kinetoplastid protozoa that devastate the health and economic well-being of millions of people in Africa through the disease human African trypanosomiasis (HAT). New chemotherapy has been eagerly awaited due to severe side effects and the drug resistance issues plagu...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Kwofie, Kofi D., Tung, Nguyen Huu, Suzuki-Ohashi, Mitsuko, Amoa-Bosompem, Michael, Adegle, Richard, Sakyiamah, Maxwell M., Ayertey, Frederick, Owusu, Kofi Baffour-Awuah, Tuffour, Isaac, Atchoglo, Philip, Frempong, Kwadwo K., Anyan, William K., Uto, Takuhiro, Morinaga, Osamu, Yamashita, Taizo, Aboagye, Frederic, Appiah, Alfred A., Appiah-Opong, Regina, Nyarko, Alexander K., Yamaguchi, Yasuchika, Edoh, Dominic, Koram, Kwadwo A., Yamaoka, Shoji, Boakye, Daniel A., Ohta, Nobuo, Shoyama, Yukihiro, Ayi, Irene
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879371/
https://ncbi.nlm.nih.gov/pubmed/26953191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01916-15
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