Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

The inflammasome is hypothesized to be a key mediator of the response to physiological and psychological stressors, and its dysregulation may be implicated in major depressive disorder. Inflammasome activation causes the maturation of caspase-1 and activation of interleukin (IL)-1β and IL-18, two pr...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Wong, M-L, Inserra, A, Lewis, M D, Mastronardi, C A, Leong, L, Choo, J, Kentish, S, Xie, P, Morrison, M, Wesselingh, S L, Rogers, G B, Licinio, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879188/
https://ncbi.nlm.nih.gov/pubmed/27090302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.46
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