Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner

BACKGROUND AND AIM: Angiogenesis is emerging as a pivotal process in chronic inflammatory pathologies, promoting immune infiltration and prompting carcinogenesis. Ulcerative Colitis (UC) and Crohn’s Disease (CD) represent paradigmatic examples of intestinal chronic inflammatory conditions in which t...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sarnelli, Giovanni, D’Alessandro, Alessandra, Iuvone, Teresa, Capoccia, Elena, Gigli, Stefano, Pesce, Marcella, Seguella, Luisa, Nobile, Nicola, Aprea, Giovanni, Maione, Francesco, de Palma, Giovanni Domenico, Cuomo, Rosario, Steardo, Luca, Esposito, Giuseppe
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878779/
https://ncbi.nlm.nih.gov/pubmed/27219328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156198
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