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A Structure and Dynamics Continuum of Higher-Order Assemblies: Amyloids, Signalosomes and Granules

We here attempt to reach an integrated understanding of the structure and dynamics of a number of higher-order assemblies including amyloids, various kinds of signalosomes, and cellular granules. We propose that the synergy between folded domains, linear motifs and intrinsically disordered regions r...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Wu, Hao, Fuxreiter, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878688/
https://ncbi.nlm.nih.gov/pubmed/27203110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.004
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