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Systematic Evaluation of Sanger Validation of NextGen Sequencing Variants

BACKGROUND: Next-generation sequencing (NGS) data are used for both clinical care and clinical research. DNA sequence variants identified using NGS are often returned to patients/participants as part of clinical or research protocols. The current standard of care is to validate NGS variants using Sa...

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Bibliographic Details
Published in:Clin Chem
Main Authors: Beck, Tyler F., Mullikin, James C., Biesecker, Leslie G.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878677/
https://ncbi.nlm.nih.gov/pubmed/26847218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2015.249623
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