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Replication stress and cancer: it takes two to tango
Problems arising during DNA replication require the activation of the ATR-CHK1 pathway to ensure the stabilization and repair of the forks, and to prevent the entry into mitosis with unreplicated genomes. Whereas the pathway is essential at the cellular level, limiting its activity is particularly d...
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| Publicado no: | Exp Cell Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878650/ https://ncbi.nlm.nih.gov/pubmed/25257608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.09.019 |
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