Chargement en cours...

Replication stress and cancer: it takes two to tango

Problems arising during DNA replication require the activation of the ATR-CHK1 pathway to ensure the stabilization and repair of the forks, and to prevent the entry into mitosis with unreplicated genomes. Whereas the pathway is essential at the cellular level, limiting its activity is particularly d...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Exp Cell Res
Auteurs principaux: Lecona, Emilio, Fernández-Capetillo, Oscar
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878650/
https://ncbi.nlm.nih.gov/pubmed/25257608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.09.019
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!