Disruption of ribosome assembly in yeast blocks cotranscriptional pre-rRNA processing and affects the global hierarchy of ribosome biogenesis

In higher eukaryotes, pre-rRNA processing occurs almost exclusively post-transcriptionally. This is not the case in rapidly dividing yeast, as the majority of nascent pre-rRNAs are processed cotranscriptionally, with cleavage at the A(2) site first releasing a pre-40S ribosomal subunit followed by r...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Talkish, Jason, Biedka, Stephanie, Jakovljevic, Jelena, Zhang, Jingyu, Tang, Lan, Strahler, John R., Andrews, Philip C., Maddock, Janine R., Woolford, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878612/
https://ncbi.nlm.nih.gov/pubmed/27036125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055780.115
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