Thy1(+)IL-7(+) lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation

Memory CD4(+) T helper (Th) cells are central to long-term protection against pathogens, but they can also be pathogenic and drive chronic inflammatory disorders. How these pathogenic memory Th cells are maintained, particularly at sites of local inflammation, remains unclear. We found that ectopic...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Shinoda, Kenta, Hirahara, Kiyoshi, Iinuma, Tomohisa, Ichikawa, Tomomi, Suzuki, Akane S., Sugaya, Kaoru, Tumes, Damon J., Yamamoto, Heizaburo, Hara, Takahiro, Tani-ichi, Shizue, Ikuta, Koichi, Okamoto, Yoshitaka, Nakayama, Toshinori
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878506/
https://ncbi.nlm.nih.gov/pubmed/27140620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512600113
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