Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver

Hypoxia and iron both regulate metabolism through multiple mechanisms, including hypoxia-inducible transcription factors. The hypoxic effects on glucose disposal and glycolysis are well established, but less is known about the effects of hypoxia and iron deficiency on hepatic gluconeogenesis. We the...

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Veröffentlicht in:Diabetes
Hauptverfasser: Nam, Hyeyoung, Jones, Deborah, Cooksey, Robert C., Gao, Yan, Sink, Sandy, Cox, James, McClain, Donald A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2016
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878425/
https://ncbi.nlm.nih.gov/pubmed/26993063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0580
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