Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia

Preterm neonates are susceptible to perinatal hypoxic-ischemic brain injury, for which no treatment is available. In a preclinical animal model of hypoxic-ischemic brain injury in ovine fetuses, we have demonstrated the neuroprotective potential of systemically administered mesenchymal stromal cells...

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Publicat a:Stem Cells Transl Med
Autors principals: Ophelders, Daan R.M.G., Wolfs, Tim G.A.M., Jellema, Reint K., Zwanenburg, Alex, Andriessen, Peter, Delhaas, Tammo, Ludwig, Anna-Kristin, Radtke, Stefan, Peters, Vera, Janssen, Leon, Giebel, Bernd, Kramer, Boris W.
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2016
Matèries:
Cell-Based Drug Development, Screening, and Toxicology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878333/
https://ncbi.nlm.nih.gov/pubmed/27160705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0197
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