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Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets

Monomethyladenines have effects on DNA repair, G-protein-coupled receptor antagonism and autophagy. In islet ß-cells, 3-methyladenine (3-MA) has been implicated in DNA-repair and autophagy, but its mechanism of action is unclear. Here, the effect of monomethylated adenines was examined in rat islets...

詳細記述

保存先:
書誌詳細
出版年:Islets
主要な著者: Boland, Brandon B, Alarcón, Cristina, Ali, Almas, Rhodes, Christopher J
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878263/
https://ncbi.nlm.nih.gov/pubmed/26404841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2015.1073435
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