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Beta cell specific probing with fluorescent exendin-4 is progressively reduced in type 2 diabetic mouse models
Probes based on GLP-1R agonist exendin-4 have shown promise as in vivo β cell tracers. However, questions remain regarding the β cell specificity of exendin-4 probes, and it is unclear if the expression levels of the GLP-1R are affected in a type 2 diabetic state. Using in vivo probing followed by e...
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| Pubblicato in: | Islets |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878261/ https://ncbi.nlm.nih.gov/pubmed/26963143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2015.1137415 |
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