Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway

BACKGROUND: Excessive autophagy induced by extravagant oxidative stress is the main reason for diabetes-induced vascular endothelial cells dysfunction. Hydrogen sulfide (H(2)S) has anti-oxidative effects but its regulation on excessive autophagy of vascular endothelial cells is unclear. METHODS: In...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Liu, Jiaqi, Wu, Jichao, Sun, Aili, Sun, Yu, Yu, Xiangjing, Liu, Ning, Dong, Shiyun, Yang, Fan, Zhang, Linxue, Zhong, Xin, Xu, Changqing, Lu, Fanghao, Zhang, Weihua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877995/
https://ncbi.nlm.nih.gov/pubmed/27222705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0099-1
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