Dasatinib (BMS-35482) potentiates the activity of gemcitabine and docetaxel in uterine leiomyosarcoma cell lines

BACKGROUND: To explore the activity of dasatinib alone and in combination with gemcitabine and docetaxel in uterine leiomyosarcoma (uLMS) cell lines, and determine if dasatinib inhibits the SRC pathway. METHODS: SK-UT-1 and SK-UT-1B uLMS cells were treated with gemcitabine, docetaxel and dasatinib i...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol Res Pract
Main Authors: Lopez-Acevedo, Micael, Grace, Lisa, Teoh, Deanna, Whitaker, Regina, Adams, David J, Jia, Jingquan, Nixon, Andrew B, Secord, Angeles Alvarez
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877815/
https://ncbi.nlm.nih.gov/pubmed/27231555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2053-6844-1-2
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