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l-Amino acid oxidase isolated from Calloselasma rhodostoma snake venom induces cytotoxicity and apoptosis in JAK2V617F-positive cell lines

BACKGROUND: Myeloproliferative neoplasms are Philadelphia chromosome-negative diseases characterized by hyperproliferation of mature myeloid cells, associated or not with the Janus kinase 2 tyrosine kinase mutation, JAK2V617F. As there is no curative therapy, researchers have been investigating new...

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Detalhes bibliográficos
Publicado no:Rev Bras Hematol Hemoter
Main Authors: Tavares, Cristiane, Maciel, Thaís, Burin, Sandra, Ambrósio, Luciana, Ghisla, Sandro, Sampaio, Suely, Castro, Fabíola
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Hematologia e Hemoterapia 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877619/
https://ncbi.nlm.nih.gov/pubmed/27208571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjhh.2016.03.004
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