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Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation

Cadherin switching from E-cadherin (E-cad) to N-cadherin (N-cad) is a key step of the epithelial-mesenchymal transition (EMT) processes that occurs during gastrulation and cancer progression. We investigate whether cadherins actively participate in progression of EMT by crosstalk to signaling pathwa...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Basilicata, M. Felicia, Frank, Marcus, Solter, Davor, Brabletz, Thomas, Stemmler, Marc P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877576/
https://ncbi.nlm.nih.gov/pubmed/27217206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26562
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