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siRNA Versus miRNA as Therapeutics for Gene Silencing

Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs (miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently been investigated as novel classes of therapeutic agents for the treatment of a wide range of disorders including cancers an...

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Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Lam, Jenny K W, Chow, Michael Y T, Zhang, Yu, Leung, Susan W S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877448/
https://ncbi.nlm.nih.gov/pubmed/26372022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.23
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