Early and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion

β-Cell regeneration is a key goal of diabetes research. Progression through the cell cycle is associated with retinoblastoma protein (pRb) inactivation via sequential phosphorylation by the “early” cyclins and cyclin-dependent kinases (cdks) (d-cyclins cdk4/6) and the “late” cyclins and cdks (cyclin...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Tiwari, Shiwani, Roel, Chris, Wills, Rachel, Casinelli, Gabriella, Tanwir, Mansoor, Takane, Karen K., Fiaschi-Taesch, Nathalie M.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2015
Teme:
Islet Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876788/
https://ncbi.nlm.nih.gov/pubmed/26159177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1885
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki