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Antimanic Treatment With Tamoxifen Affects Brain Chemistry: A Double-Blind, Placebo-Controlled Proton Magnetic Resonance Spectroscopy Study

BACKGROUND: The antimanic efficacy of a protein kinase C (PKC) inhibitor, tamoxifen, has been tested in several clinical trials, all reporting positive results. However, mechanisms underlying the observed clinical effects requires further confirmation through studies of biological markers. METHODS:...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry Cogn Neurosci Neuroimaging
Main Authors: Yildiz, Ayşegül, Aydin, Burç, Gökmen, Necati, Yurt, Ayşegül, Cohen, Bruce, Keskinoglu, Pembe, Öngür, Dost, Renshaw, Perry
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876725/
https://ncbi.nlm.nih.gov/pubmed/27231722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpsc.2015.12.002
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