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PCSK7 Genotype Modifies Effect of a Weight-Loss Diet on 2-Year Changes of Insulin Resistance: The POUNDS LOST Trial

OBJECTIVE: A common variant rs236918 in the PCSK7 gene has the strongest association with iron homeostasis and is related to insulin resistance. Dietary carbohydrate (CHO) modulates the genetic effect on insulin resistance. We examined whether 2-year weight-loss diets modify the effect of PCSK7 gene...

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Détails bibliographiques
Publié dans:Diabetes Care
Auteurs principaux: Huang, Tao, Huang, Jinyan, Qi, Qibin, Li, Yanping, Bray, George A., Rood, Jennifer, Sacks, Frank M., Qi, Lu
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876697/
https://ncbi.nlm.nih.gov/pubmed/25504030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc14-0473
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