A protein kinase associated with paired helical filaments in Alzheimer disease.
We have identified a protein kinase in immunoaffinity-purified preparations of paired helical filaments from brain tissue of individuals with Alzheimer disease. The kinase phosphorylates the filament proteins in vitro in a manner independent of second messenger regulation or of modulation by heparin...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48766/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557394/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2878 |
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