Epigenetic Upregulation of Metallothionein 2A by Diallyl Trisulfide Enhances Chemosensitivity of Human Gastric Cancer Cells to Docetaxel Through Attenuating NF-κB Activation

Aims: Metallothionein 2A (MT2A) and nuclear factor-kappaB (NF-κB) are both involved in carcinogenesis and cancer chemosensitivity. We previously showed decreased expression of MT2A and IκB-α in human gastric cancer (GC) associated with poor prognosis of GC patients. The present study investigated th...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Pan, Yuanming, Lin, Shuye, Xing, Rui, Zhu, Min, Lin, Bonan, Cui, Jiantao, Li, Wenmei, Gao, Jing, Shen, Lin, Zhao, Yuanyuan, Guo, Mingzhou, Wang, Ji Ming, Huang, Jiaqiang, Lu, Youyong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876530/
https://ncbi.nlm.nih.gov/pubmed/26801633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6128
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