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Two-Photon Enzymatic Probes Visualizing Sub-cellular/Deep-brain Caspase Activities in Neurodegenerative Models

Caspases work as a double-edged sword in maintaining cell homeostasis. Highly regulated caspase activities are essential during animal development, but dysregulation might lead to different diseases, e.g. extreme caspase activation is known to promote neurodegeneration. At present, visualization of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Qian, Linghui, Zhang, Cheng-Wu, Mao, Yanli, Li, Lin, Gao, Nengyue, Lim, Kah-Leong, Xu, Qing-Hua, Yao, Shao Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876444/
https://ncbi.nlm.nih.gov/pubmed/27210613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26385
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