Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells

Anoctamin-1 (ANO1) acts as a Ca(2+)-activated Cl(−) channel in various normal tissues, and its expression is increased in several different types of cancer. Therefore, understanding the regulation of ANO1 surface expression is important for determining its physiological and pathophysiological functi...

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Publicado no:Sci Rep
Main Authors: Lee, Young-Sun, Lee, Jae Kwang, Bae, Yeonju, Lee, Bok-Soon, Kim, Eunju, Cho, Chang-Hoon, Ryoo, Kanghyun, Yoo, Jiyun, Kim, Chul-Ho, Yi, Gwan-Su, Lee, Seok-Geun, Lee, C. Justin, Kang, Sang Soo, Hwang, Eun Mi, Park, Jae-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876403/
https://ncbi.nlm.nih.gov/pubmed/27212225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26413
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