Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians

AIM: To examine whether strict control of clinical trial conditions could reduce apparent differences of pharmacokinetic (PK) parameters among ethnic groups. METHODS: Open‐label, single dose PK studies of moxifloxacin, simvastatin and meloxicam were conducted in healthy male subjects from three East...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Hasunuma, Tomoko, Tohkin, Masahiro, Kaniwa, Nahoko, Jang, In‐Jin, Yimin, Cui, Kaneko, Masaru, Saito, Yoshiro, Takeuchi, Masahiro, Watanabe, Hiroshi, Yamazoe, Yasushi, Uyama, Yoshiaki, Kawai, Shinichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876172/
https://ncbi.nlm.nih.gov/pubmed/26774055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12884
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