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Non-enzymatic glycation and degree of mineralization are higher in bone from fractured patients with Type 1 Diabetes Mellitus

OBJECTIVE: Low-energy fractures are frequent complications in Type 1 Diabetes Mellitus patients (T1DM). Modifications of bone intrinsic composition might be a potential cause of fragility observed in diabetic subjects. Advanced Glycation End-products (AGEs) were found in numerous connective tissues...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Farlay, D, Armas, L, Gineyts, E, Akhter, M, Recker, R, Boivin, G
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876148/
https://ncbi.nlm.nih.gov/pubmed/26234180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2607
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