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Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase

Coenzyme A (CoA)-transferases catalyze the reversible transfer of CoA from acyl-CoA thioesters to free carboxylates. Class I CoA-transferases produce acylglutamyl anhydride intermediates that undergo attack by CoA thiolate on either the internal or external carbonyl carbon atoms, forming distinct te...

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Détails bibliographiques
Publié dans:Front Chem
Auteurs principaux: Murphy, Jesse R., Mullins, Elwood A., Kappock, T. Joseph
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876117/
https://ncbi.nlm.nih.gov/pubmed/27242998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00023
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