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Clinical efficacy of perampanel for partial-onset and primary generalized tonic–clonic seizures

BACKGROUND AND PURPOSE: Perampanel, a selective noncompetitive antagonist at the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor, is highly effective in a wide range of experimental models. Although initially licensed as adjunctive therapy for partial seizures with or without se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychiatr Dis Treat
Hauptverfasser: Besag, Frank MC, Patsalos, Philip N
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876101/
https://ncbi.nlm.nih.gov/pubmed/27274257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S83842
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