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Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach

BACKGROUND AND OBJECTIVES: Oxycodone is the mo st commonly used opioid for the treatment of moderate to severe pain. The peak cerebrospinal fluid concentration after epidural oxycodone was reported to be 300-fold greater (0.025 mM) than when administered intravenously after gynecologic surgery. Addi...

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Détails bibliographiques
Publié dans:Drugs R D
Auteurs principaux: Kokki, Merja, Pesonen, Maija, Vehviläinen, Piia, Litmala, Outi, Pasanen, Markku, Kokki, Hannu
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875920/
https://ncbi.nlm.nih.gov/pubmed/26913723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-016-0125-0
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