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Biglycan potentially regulates angiogenesis during fracture repair by altering expression and function of endostatin

The small proteoglycan biglycan (Bgn) is highly expressed in the organic matrix of bone and plays a role in bone formation. Previous work implicated Bgn in vessel growth during bone healing (1). By infusing barium sulfate (BaSO(4)) into WT and Bgn-deficient mice we discovered the positive effect of...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Myren, Maja, Kirby, David J., Noonan, Megan L., Maeda, Azusa, Owens, Rick T., Ricard-Blum, Sylvie, Kram, Vardit, Kilts, Tina M., Young, Marian F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875882/
https://ncbi.nlm.nih.gov/pubmed/27072616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.03.008
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